Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ Pyr3
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CAS: 1160514-60-2 Molecular Formula: C16H11Cl3F3N3O3
| CAS | 1160514-60-2 |
|---|---|
| Molecular Formula | C16H11Cl3F3N3O3 |
Tocris Bioscience™ GW 2580
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Selective cFMS kinase inhibitor; orally bioavailable
| Target | Additional RTK Inhibitors |
|---|---|
| CAS | 870483-87-7 |
| Purity | >99% |
| Chemical Name or Material | 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H22N4O3 |
| Formula Weight | 366.41 |
Tocris Bioscience™ AP 24534
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CAS: 943319-70-8 Molecular Formula: C29H27F3N6O
| CAS | 943319-70-8 |
|---|---|
| Molecular Formula | C29H27F3N6O |
Tocris Bioscience™ L-741,626
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CAS: 81226-60-0 Molecular Formula: C20H21ClN2O
| CAS | 81226-60-0 |
|---|---|
| Molecular Formula | C20H21ClN2O |
Tocris Bioscience™ Ionomycin calcium salt
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CAS: 56092-82-1 Molecular Formula: C41H70CaO9
| CAS | 56092-82-1 |
|---|---|
| Molecular Formula | C41H70CaO9 |
Tocris Bioscience™ Ruxolitinib phosphate
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Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
Tocris Bioscience™ Ebselen
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Glutathione peroxidase mimic; peroxynitrite scavenger
| Inhibitors | Ebselen |
|---|---|
| CAS | 60940-34-3 |
| Product Type | Ebselen |
| Molecular Weight (g/mol) | M.W. (Observed): 274.18 |
| Purity | 98% |
| Recommended Storage | -20°C |
| Molecular Formula | 2-Phenyl-1,2-benzisoselenazol-3(2 H)-one |
Tocris Bioscience™ Deferoxamine mesylate
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Iron chelator; also hypoxia mimetic
Tocris Bioscience™ AZD 7648
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Potent and selective DNA-PK inhibitor
| Target | DNA-dependent Protein Kinase Inhibitors |
|---|---|
| CAS | 2230820-11-6 |
| Chemical Name or Material | 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C18H20N8O2 |
Tocris Bioscience™ CASIN
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Cdc42 inhibitor
| Product Type | CASIN |
|---|---|
| Molecular Weight (g/mol) | 306.4 |
| Purity | >98% |
Tocris Bioscience™ Talampanel
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Non-competitive AMPA/kainate antagonist
Tocris Bioscience™ CP 945598 hydrochloride
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CAS: 686347-12-6 Molecular Formula: C25H26Cl3N7O
| CAS | 686347-12-6 |
|---|---|
| Molecular Formula | C25H26Cl3N7O |
Tocris Bioscience™ Maraviroc
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CAS: 376348-65-1 Molecular Formula: C29H41F2N5O
| CAS | 376348-65-1 |
|---|---|
| Molecular Formula | C29H41F2N5O |
Tocris Bioscience™ Pomalidomide 4'-alkylC3-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Tocris Bioscience™ SKF 96365 hydrochloride
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CAS: 130495-35-1 Molecular Formula: C22H27ClN2O3
| CAS | 130495-35-1 |
|---|---|
| Molecular Formula | C22H27ClN2O3 |